Structure of PDB 8ro2 Chain L2

Receptor sequence
>8ro2L2 (length=369) Species: 9606 (Homo sapiens) [Search protein sequence]
GEDTWMLPDVNERIEQFSQEHSSGVENEDQQEVILVRTDQSGRVWPVNTK
RQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMASKF
MGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKKAIAEHRSLAAQMEKC
LYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHRAATLL
DEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPK
EVGDMAPIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDF
GLHGGFAHVIEDQHKFPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKK
ALQFAQWWKPYDFTKSKNY
3D structure
PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
ChainL2
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna L2 I662 R666 I137 R141
BS02 rna L2 K575 F625 K50 F100
BS03 rna L2 R647 R658 K659 H839 R866 R122 R133 K134 H314 R341
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ2TBE0|C19L2_HUMAN CWF19-like protein 2 (Gene Name=CWF19L2)

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