Structure of PDB 9bkd Chain L

Receptor sequence

>9bkdL (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]

DKEWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEV
LKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAII
LAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVS
APVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLW
KETVFTKSPYQEFTDHLVKT

3D structure

PDB

9bkd Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	L	M110 Q113 K114 Q115 T116 R117 A118 R121 R123 K125 K142 K145 T185 R187 C188 G189 S190 R194 V205 S206 A207 Y223 T224 R227 C229 T230 T232 N235 F236 K238	M54 Q57 K58 Q59 T60 R61 A62 R65 R67 K69 K86 K89 T129 R131 C132 G133 S134 R138 V149 S150 A151 Y167 T168 R171 C173 T174 T176 N179 F180 K182

External links

PDB	RCSB:9bkd, PDBe:9bkd, PDBj:9bkd
PDBsum	9bkd
PubMed	39117603
UniProt	P15880\|RS2_HUMAN Small ribosomal subunit protein uS5 (Gene Name=RPS2)

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