Structure of PDB 8wha Chain L

Receptor sequence
>8whaL (length=452) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
KSYQLKGVKWLISLWQNGLNGILADQMGLGKTIQTIGFLSHLKGNGLDGP
YLVIAPLSTLSNWFNEIARFTPSINAIIYHGDKNQRDELRRKHMPKTVGP
KFPIVITSYEVAMNDAKRILRHYPWKYVVIDEGHRLKNHKCKLLRELKHL
KMDNKLLLTGTPLQNNLSELWSLLNFILPDIFTSHDEFESQVVSKLHGIL
RPFILRRMKCDVELSLPRKKEIIMYATMTDHQKKFQEHLVNNTLEAHLGE
NAIRGQGWKGKLNNLVIQLRKNCNHPDLLQGQIDGSYLYPPVEEIVGQCG
KFRLLERLLVRLFANNHKVLIFSQWTKLLDIMDYYFSEKGFEVCRIDGSV
KLDERRRQIKDFSDEKSSCSIFLLSTRAGGLGINLTAADTCILYDSDWNP
QMDLQAMDRCHRIGQTKPVHVYRLSTAQSIETRVLKRAYSKLKLEHVVIG
QG
3D structure
PDB8wha Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
ChainL
Resolution4.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna L L259 D284 E312 N487 W549 G572 A602 L57 D82 E110 N263 W325 G348 A378
BS02 dna L K339 N340 C343 K344 W622 N623 K137 N138 C141 K142 W398 N399
BS03 BEF L K233 R636 K31 R412
BS04 ADP L Q206 G232 K233 T234 R271 R636 I637 Q4 G30 K31 T32 R69 R412 I413
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006346 DNA methylation-dependent heterochromatin formation
GO:0009294 DNA-mediated transformation
GO:0031507 heterochromatin formation
GO:0032197 retrotransposition
GO:0032508 DNA duplex unwinding
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8wha, PDBe:8wha, PDBj:8wha
PDBsum8wha
PubMed38413824
UniProtQ9XFH4|DDM1_ARATH ATP-dependent DNA helicase DDM1 (Gene Name=DDM1)

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