Structure of PDB 8sps Chain L

Receptor sequence
>8spsL (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]
KALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEA
LQLSFKNMCKLRPLLQKWVEEADNN
3D structure
PDB8sps Structural mechanism of LIN28B nucleosome targeting by OCT4.
ChainL
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna L T163 Q164 Q181 T182 C185 T24 Q25 Q42 T43 C46
BS02 dna L T182 R186 L192 S193 N196 T43 R47 L53 S54 N57
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:8sps, PDBe:8sps, PDBj:8sps
PDBsum8sps
PubMed37327775
UniProtQ01860|PO5F1_HUMAN POU domain, class 5, transcription factor 1 (Gene Name=POU5F1)

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