Structure of PDB 8s4k Chain L

Receptor sequence

>8s4kL (length=216) Species: 10090 (Mus musculus) [Search protein sequence]

DIVITQDELSNPVTSGESVSISCRSSKSLLYKDGKTYLNWFLQRPGQSPQ
LLIYLMSTRASGVSDRFSGSGSGTDFTLEISRVKAEDVGVYYCQQLVEYP
YTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDIN
VKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE
ATHKTSTSPIVKSFNR

3D structure

PDB

8s4k Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

Chain

Resolution

1.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	RBR	L	Y27D Y32 L91 V92 E93 Y94 Y96	Y31 Y37 L96 V97 E98 Y99 Y101

External links

PDB	RCSB:8s4k, PDBe:8s4k, PDBj:8s4k
PDBsum	8s4k
PubMed	39259810

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