Structure of PDB 8qav Chain L

Receptor sequence
>8qavL (length=184) Species: 3880 (Medicago truncatula) [Search protein sequence]
ARIGEMKRVTKETNVSVKINLDGTGVADNSSGIPFLDHMLDQLASHGLFD
VHVKATGDTHIDDHHTNEDVALAIGTALLQALGDRKGINRFGNFSAPLDE
ALVHVSLDLSGRPHLGYDLNIPTQRVGKYDTQLVEHFFQSLVNTSGMTLH
IRQFSGTNSHHIIEATFKAFARALRQATEYDTRR
3D structure
PDB8qav Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting.
ChainL
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IG2 L H141 H142 H64 H65
BS02 MN L H141 E145 H213 H64 E68 H136
BS03 MN L H115 H237 E241 H38 H160 E164
Gene Ontology
Molecular Function
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Biological Process
GO:0000105 L-histidine biosynthetic process

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:8qav, PDBe:8qav, PDBj:8qav
PDBsum8qav
PubMed38559763
UniProtA0A072VQG6

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