Structure of PDB 8ovd Chain L

Receptor sequence

>8ovdL (length=551) Species: 1772 (Mycolicibacterium smegmatis)

ELEARRPFPERMGPKGNLIYKLITTTDHKLIGIMYCVVCFAFFLVGGLMA
LFMRTELAMPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVFGFANLVLPL
QIGAPDVAFPRLNALSFWLFLFGALIAIAGFITPGGAADFGWTAYSPLTD
AIHSPGAGGDLWIMGLAVGGLGTILGGVNMITTVVCMRAPGMTMFRMPIF
TWNILVTSILVLIAFPILTAALFGLAADRHLGAHIYDPANGGVLLWQHLF
WFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLAIAALSVA
VWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPM
LFSVGFLITFLLGGLSGVLLASPPLDFHVTDSYFVIAHFHYVLFGTIVFA
TYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTTFLVQHWLGDEGMPR
RYADYLPTDGFTTLNVISTVGAFILGVSMLPFVWNVFKSWRYGEPVTVDD
PWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAH
V

3D structure

• PDB: 8ovd Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex.
• Chain: L
• Resolution: 2.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MQ9	L	L134 I135 A138	L125 I126 A129
BS02	HEA	L	W260 V267 H313 H314 T337 G338 G373 G376 L379 D385 T389 V394 H397 F398 V401 L402 R459	W251 V258 H304 H305 T328 G329 G364 G367 L370 D376 T380 V385 H388 F389 V392 L393 R450
BS03	HEA	L	F52 G56 L57 A59 R63 F79 F83 H86 G87 M90 L91 W151 Y392 I395 F398 H399 L402 F403 I406 F446 R459 R460 L484 M488	F43 G47 L48 A50 R54 F70 F74 H77 G78 M81 L82 W142 Y383 I386 F389 H390 L393 F394 I397 F437 R450 R451 L475 M479
BS04	CU	L	H264 H313 H314	H255 H304 H305
BS05	CA	L	E65 M68 G70 Q72	E56 M59 G61 Q63

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006119 oxidative phosphorylation
• GO:0009060 aerobic respiration
• GO:0015990 electron transport coupled proton transport
• GO:0022904 respiratory electron transport chain

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:8ovd, PDBe:8ovd, PDBj:8ovd
• PDBsum: 8ovd
• PubMed: 38902248
• UniProt: A0A2U9PNL2