Structure of PDB 8oh5 Chain L

Receptor sequence

>8oh5L (length=1172) Species: 1123288 (Sporomusa ovata DSM 2662)

MSKISININGRELVVSAGQTILQAAAEHGIEIPHLCHDERIQPYGACGLC
VVEVEGSPKLVRSCATSVQNGQVIRTDTSRTVVARKTALQLLASDHRGDC
RPPCMLACPAQTDCQGYVGLIANGQYEEALKLIKDKMPIPASIGKICPHP
CETACRRELVEEPISIAQLKSFVAEVDLNGNQYQPPMKPATGKKVAVVGA
GPAGLTAAYFLARDGHKVVIYEAMPHPGGMLRYGIPQYRLDKALLDAEVA
LMTKMGIEIIYNTKIGDDVSLDYLHDNYDAVFLGIGSWQSQGLRCKGEDM
EGVLGGIDFLREVTMNSNITLGGKVLVVGGGNTAMDVARTSKRLGAEEVT
IIYRRTIDEMPAEKIEIHEAQEEGVKFQLLVAPVEVLGENGHAKALKCEI
MRLGEPDASGRRKPEPTGETVVYEADRIIAAIGQKTVIGNIKDIATDKSG
NIIVNGGAFTTNRDKVFAGGDAVTGPKIAIDAIAQGKNAAQVIDSYLNGC
LVPHADSQYFTQKDITAADLADRAKAPRVSLTVEDAEVRNKSFMQVAKTF
TEEEALRESKRCLECGCRDYFECQLIKYIQDYDVSTEKDSQVECHKTTEF
DNHPFIERNPDKCVLCGLCVRVCDEVVGATAIGLVGRGFDSVIMPEFKLP
LSETACISCGQCVDVCPTGACMEKQVSYKQIPANMDSMASVCGYCGVGCN
VNIEYKGDVVFRVTPDRVNDDGWLCQRGKFGLGHANDKARLTAPVIKRNG
QFVKVDWNEANLEVVKRLQAVVAAYGKDSIGVVVSPRLTNEELFLAGKLA
DAVNTTIKTSYSVDGGSGLGSVLGYDASTNSFAELDNSDFVLTLGKVKEN
HPVLDFKIRLSGVCSVAWPQSLANTADMKVFLKALLNLGVDENKVAEKTE
GFAELKASLADVKVSEEIQALAQKYAKAAKPLIVIDEDTVSAEAVKLMAY
AAVITGKIGAAYRGIILVRTKNNTQGAVDMGFVMPVSAVAQGIESGKIKA
LVVIGEDPAAYPQESALLQKLSFLVVYDMFMTKTATAADMVVPLVSSAEV
NGTYTRSDRRIQAVRAAIQPKTGKATLQILIETLKSLGIKYDTIADVRAA
IASEVSNYAGMDAADFGTTVYWPNNKNVLYTDGFATEGQKAILAAVGDVP
VFVEKKKYDSVEMNFVNGRQSL

3D structure

• PDB: 8oh5 Molecular architecture and electron transfer pathway of the Stn family transhydrogenase.
• Chain: L
• Resolution: 3.0 Å

Enzymatic activity

• Enzyme Commision number: 1.2.1.2: Transferred entry: 1.17.1.9.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	L	G199 G201 P202 A203 E222 A223 G229 M230 I235 R239 K264 I265 I285 W288 N332 D471 K477 A479	G199 G201 P202 A203 E222 A223 G229 M230 I235 R239 K264 I265 I285 W288 N332 D471 K477 A479
BS02	SF4	L	C613 V614 L615 C616 G617 C619 I643 C666 A670	C613 V614 L615 C616 G617 C619 I643 C666 A670
BS03	NDP	L	G330 G331 N332 T333 Y353 R354 R355 I432 G433 Q434 K477	G330 G331 N332 T333 Y353 R354 R355 I432 G433 Q434 K477
BS04	SF4	L	P102 C104 C155 R156 I164 C562 L563 C565	P102 C104 C155 R156 I164 C562 L563 C565
BS05	SF4	L	H96 G98 C100 C567 C573 G669	H96 G98 C100 C567 C573 G669
BS06	SF4	L	C108 C147 H149 C151 K170 I480	C108 C147 H149 C151 K170 I480
BS07	SF4	L	C623 C656 I657 S658 C659 G660 C662	C623 C656 I657 S658 C659 G660 C662
BS08	SF4	L	C692 Y694 C695 C699 C725 R727 G728 V853	C692 Y694 C695 C699 C725 R727 G728 V853
BS09	FES	L	C36 G45 C47 G48 C50 C64	C36 G45 C47 G48 C50 C64

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding

External links

• PDB: RCSB:8oh5, PDBe:8oh5, PDBj:8oh5
• PDBsum: 8oh5
• PubMed: 37673911
• UniProt: A0A0U1KYI6