Structure of PDB 8idt Chain L

Receptor sequence

>8idtL (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]

PSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGLHHHRINFDKYHPG
YFGKVGMKHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGAAPII
DVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKSVGGACVLVA

3D structure

PDB

8idt Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

2.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	L	P2 S3 R4 R6 K7 T8 R9 K10 R12 H14 V15 S16 H17 G18 H19 G20 R21 I22 H25 R26 K27 P29 G30 G31 R32 G33 N34 G36 H39 H40 H41 R42 I43 N44 K47 Y52 F53 G54 K55 G57 M58 K59 H60 Y61 H62 L63 K64 N74 V82 S83 Q85 T86 D102 R105 L112 G113 K114 G115 K116 R131 R132	P1 S2 R3 R5 K6 T7 R8 K9 R11 H13 V14 S15 H16 G17 H18 G19 R20 I21 H24 R25 K26 P28 G29 G30 R31 G32 N33 G35 H38 H39 H40 R41 I42 N43 K46 Y51 F52 G53 K54 G56 M57 K58 H59 Y60 H61 L62 K63 N73 V81 S82 Q84 T85 D101 R104 L111 G112 K113 G114 K115 R130 R131

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8idt, PDBe:8idt, PDBj:8idt
PDBsum	8idt
PubMed	37491604
UniProt	P46776\|RL27A_HUMAN Large ribosomal subunit protein uL15 (Gene Name=RPL27A)