Structure of PDB 8hla Chain L

Receptor sequence
>8hlaL (length=215) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence]
MVVIGEKFPEVEVKTTHGVIKLPDYFAEQGKWFVLFSHPADCTPVSTTEF
YAMQKRVDQFRELGVEPIGLSVDQVFSHIKWMEWIKENLGEEITFPVIAD
DRGELADKLGMIPSGATITARAVFIVDDKGIIRAIVYYPAEVGRDWDEIL
RLVKALKVSDEKGVALPHKWPNNELIGDKAIVPPASTVDEVKQREEAKAK
GEIESYDWWFSYKKL
3D structure
PDB8hla Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
ChainL
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.24: thioredoxin-dependent peroxiredoxin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FL3 L P184 W209 P184 W209
BS02 FL3 L K80 W81 W84 K80 W81 W84
BS03 FL3 L C42 E141 C42 E141
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0051920 peroxiredoxin activity
GO:0140824 thioredoxin-dependent peroxiredoxin activity
Biological Process
GO:0045454 cell redox homeostasis
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:8hla, PDBe:8hla, PDBj:8hla
PDBsum8hla
PubMed36888722
UniProtQ5JF30|TDXH_THEKO Peroxiredoxin (Gene Name=TK0537)

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