Structure of PDB 7tr8 Chain L

Receptor sequence
>7tr8L (length=336) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
MYVRISGRIRLNAHSLNAQGGGGTNYIEITKTKVTVRTENGWTVVEVPAI
TGNMLKHWHFVGFVDYFKTTPYGVNLTERALRYNGTRFGQGETTATKANG
ATVQLNDEATIIKELADADVHGFLAPKTGRRRVSLVKASFILPTEDFIKE
VEGERLITAIKHNRVDVDEKGAIGSSKEGTAQMLFSREYATGLYGFSIVL
DLGLVGIPQGLPVKFEENQPRPNIVIDPNERKARIESALKALIPMLSGYI
GANLARSFPVFKVEELVAIASEGPIPALVHGFYEDYIEANRSIIKNARAL
GFNIEVFTYNVDLGEDIEATKVSSVEELVANLVKMV
3D structure
PDB7tr8 Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
ChainL
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna L N17 A18 Q19 G20 G22 N53 M54 G85 T86 L124 K161 N163 R164 V165 L184 F185 N253 R256 N17 A18 Q19 G20 G22 N53 M54 G85 T86 L124 K161 N163 R164 V165 L184 F185 N253 R256
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7tr8, PDBe:7tr8, PDBj:7tr8
PDBsum7tr8
PubMed35835111
UniProtQ8U333

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