Structure of PDB 7r6t Chain L

Receptor sequence
>7r6tL (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRK
HCKFKPDPNIPPTFSAFNEDYVGSGWSRGAMAPAGNNKFSSKAMAETFYL
SNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKK
IVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQP
QLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLY
LSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYE
3D structure
PDB7r6t Human EXOG possesses strong AP hydrolysis activity
ChainL
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.30.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna L R109 R138 G145 N171 R314 R49 R78 G85 N111 R254
BS02 dna L K113 S172 L311 K315 R320 K53 S112 L251 K255 R260
BS03 MG L A140 N171 A80 N111
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7r6t, PDBe:7r6t, PDBj:7r6t
PDBsum7r6t
PubMed
UniProtQ9Y2C4|EXOG_HUMAN Nuclease EXOG, mitochondrial (Gene Name=EXOG)

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