Structure of PDB 6u8k Chain L

Receptor sequence

>6u8kL (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]

SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIY
SASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYSSSPYTFG
QGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWK
VDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQ
GLSSPVTKSFNRGEC

3D structure

PDB

6u8k Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.

Chain

Resolution

2.75 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	L	Y50 Y92 S93 Y97	Y50 Y92 S93 Y97	PDBbind-CN: Kd=37nM

External links

PDB	RCSB:6u8k, PDBe:6u8k, PDBj:6u8k
PDBsum	6u8k
PubMed	31765566

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