Structure of PDB 6pwx Chain L

Receptor sequence
>6pwxL (length=82) Species: 8355 (Xenopus laevis) [Search protein sequence]
KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDA
VTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB6pwx Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainL
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna L P32 R36 P13 R17
BS02 dna L R35 R45 I46 S47 R78 K79 T80 R16 R26 I27 S28 R59 K60 T61
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pwx, PDBe:6pwx, PDBj:6pwx
PDBsum6pwx
PubMed31804488
UniProtP62799|H4_XENLA Histone H4

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