Structure of PDB 6ouo Chain L

Receptor sequence

>6ouoL (length=144) Species: 562 (Escherichia coli)

MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGF
EGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANI
IGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE

3D structure

• PDB: 6ouo The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
• Chain: L
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	L	L3 N4 L6 P8 G11 S12 K13 K14 A15 G16 K17 R18 L19 G20 R21 G22 G24 S25 K29 T30 G32 R33 G34 K36 G37 Q38 K39 R41 S42 G43 F50 E51 G52 G53 Q54 M55 Y58 R59 R60 P62 K63 F64 G65 F66 S68 R69 K70 E76 R78 N99 K109 I111 L112 T128 K129 G130	L3 N4 L6 P8 G11 S12 K13 K14 A15 G16 K17 R18 L19 G20 R21 G22 G24 S25 K29 T30 G32 R33 G34 K36 G37 Q38 K39 R41 S42 G43 F50 E51 G52 G53 Q54 M55 Y58 R59 R60 P62 K63 F64 G65 F66 S68 R69 K70 E76 R78 N99 K109 I111 L112 T128 K129 G130

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ouo, PDBe:6ouo, PDBj:6ouo
• PDBsum: 6ouo
• PubMed: 31189921
• UniProt: P02413|RL15_ECOLI Large ribosomal subunit protein uL15 (Gene Name=rplO)