Structure of PDB 6mv5 Chain L

Receptor sequence

>6mv5L (length=218) Species: 10090 (Mus musculus) [Search protein sequence]

DIVMTQAAPSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQ
LLIYRMSNLASGVPDRFSGSGSGTAFTLRISRVEAEDVGVYYCMQHLEYP
FTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGE

3D structure

PDB

6mv5 Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain.

Chain

Resolution

2.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	L	Y32 Y49 R50	Y37 Y54 R55
BS02	ZN	L	N137 N138	N142 N143
BS03	ZN	L	E79 E81	E84 E86
BS04	ZN	L	D185 H189	D190 H194
BS05	SO4	L	Q155 D185 H189	Q160 D190 H194

External links

PDB	RCSB:6mv5, PDBe:6mv5, PDBj:6mv5
PDBsum	6mv5
PubMed	30653992
UniProt	A0A097PUG4

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