Structure of PDB 6mu8 Chain L

Receptor sequence

>6mu8L (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]

SYVRPLSVALGETASISCGRQALGSRAVQWYQHRPGQAPILLIYNNQDRP
SGIPERFSGTPDINFGTRATLTISGVEAGDEADYYCHMWDSRSGFSWSFG
GATRLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAW
KADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPMQWKMHKSYSCQVTHE
GSTVEKTVAPT

3D structure

PDB

6mu8 Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

Chain

Resolution

2.993 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	L	S30 D67 I67A	S25 D62 I63
BS02	MAN	L	N50 N51 Q52 P66 D67	N45 N46 Q47 P61 D62

External links

PDB	RCSB:6mu8, PDBe:6mu8, PDBj:6mu8
PDBsum	6mu8
PubMed	30604750

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