Structure of PDB 6mtj Chain L

Receptor sequence

>6mtjL (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]

SYVRPLSVALGETASISCGRQALGSRAVQWYQHRPGQAPILLIYNNQDRP
SGIPERFSGTPDINFGTRATLTISGVEAGDEADYYCHMWDSRSGFSWSFG
GATRLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAW
KADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPMQWKMHKSYSCQVTHE
GSTVEKTVAPT

3D structure

PDB

6mtj Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

Chain

Resolution

2.336 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	L	S30 D67 I67A	S25 D62 I63
BS02	MAN	L	N50 N51 Q52 P66 D67	N45 N46 Q47 P61 D62

External links

PDB	RCSB:6mtj, PDBe:6mtj, PDBj:6mtj
PDBsum	6mtj
PubMed	30604750

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