Structure of PDB 6h0e Chain L

Receptor sequence

>6h0eL (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]

DVVMTQSPLSLPVTPGEPASISCRSSQSLLHRSGHKYLHWYLQRPGQSPQ
VLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGLYYCMQTLQTP
WTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGE

3D structure

PDB

6h0e Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau.

Chain

Resolution

1.95 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	L	H31 Y37 T99	H31 Y37 T99

External links

PDB	RCSB:6h0e, PDBe:6h0e, PDBj:6h0e
PDBsum	6h0e
PubMed	30001207

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