Structure of PDB 6de7 Chain L

Receptor sequence
>6de7L (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
TFVSVAPGQTARITCGEESLGSRSVIWYQQRPGQAPSLIIYNNNDRPSGI
PDRFSGSPGSTFGTTATLTITSVEAGDEADYYCHIWDSRRPTNWVFGEGT
TLIVLSQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKAD
SSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGST
VEKTVAPT
3D structure
PDB6de7 Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.
ChainL
Resolution4.123 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN L S30 S67A S22 S60
BS02 MAN L N52 P66 N44 P58
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex
GO:0070062 extracellular exosome
GO:0071735 IgG immunoglobulin complex
GO:0072562 blood microparticle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6de7, PDBe:6de7, PDBj:6de7
PDBsum6de7
PubMed29902444
UniProtP0DOY2|IGLC2_HUMAN Immunoglobulin lambda constant 2 (Gene Name=IGLC2)

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