Structure of PDB 6co3 Chain L

Receptor sequence

>6co3L (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]

DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYA
ASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGG
GTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKV
DNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG
LSSPVTKSFNR

3D structure

PDB

6co3 Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta.

Chain

Resolution

2.384 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	L	Y32 S91 Y92 S93 T94	Y32 S91 Y92 S93 T94

External links

PDB	RCSB:6co3, PDBe:6co3, PDBj:6co3
PDBsum	6co3
PubMed	29686315

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