Structure of PDB 5mdj Chain L

Receptor sequence
>5mdjL (length=598) Species: 381666 (Cupriavidus necator H16) [Search protein sequence]
AYATQGFNLDDRGRRIVVDPVTRIEGHMRCEVNVDANNVIRNAVSTGTMW
RGLEVILKGRDPRDAWAFVERICGVCTGCHALASVRAVENALDIRIPKNA
HLIREIMAKTLQVHDHAVHFYHLHALDWVDVMSALKADPKRTSELQQLVS
PAHPLSSAGYFRDIQNRLKRFVESGQLGPFMNGYWGSKAYVLPPEANLMA
VTHYLEALDLQKEWVKIHTIFGGKNPHPNYLVGGVPCAINLDAASAPVNM
ERLSFVKARIDEIIEFNKNVYVPDVLAIGTLYKQAGWLYGGGLAATNVLD
YGEYPNVAYNKSTDQLPGGAILNGNWDEVFPVDPRDSQQVQEFVSHSWYK
YADESVGLHPWDGVTEPNYVLGANTKGTRTRIEQIDESAKYSWIKSPRWR
GHAMEVGPLSRYILAYAHARSGNKYAERPKEQLEYSAQMINSAIPKALGL
PETQYTLKQLLPSTIGRTLARALESQYCGEMMHSDWHDLVANIRAGDTAT
ANVDKWDPATWPLQAKGVGTVAAPRGALGHWIRIKDGRIENYQCVVPTTW
NGSPRDYKGQIGAFEASLMNTPMVNPEQPVEILRTLHSFDPCLACSTH
3D structure
PDB5mdj Tracking the route of molecular oxygen in O2-tolerant membrane-bound [NiFe] hydrogenase.
ChainL
Resolution1.48 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E27 C75 C78 H82 R530 T553 C597 C600
Catalytic site (residue number reindexed from 1) E25 C73 C76 H80 R525 T548 C592 C595
Enzyme Commision number 1.12.99.6: hydrogenase (acceptor).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NFV L C75 C78 C81 H82 A528 P529 R530 L533 V551 P552 T553 C597 C600 C73 C76 C79 H80 A523 P524 R525 L528 V546 P547 T548 C592 C595
BS02 MG L E56 C549 H603 E54 C544 H598
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008901 ferredoxin hydrogenase activity
GO:0016151 nickel cation binding
GO:0016491 oxidoreductase activity
GO:0033748 hydrogenase (acceptor) activity
GO:0046872 metal ion binding
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5mdj, PDBe:5mdj, PDBj:5mdj
PDBsum5mdj
PubMed29463722
UniProtP31891|MBHL_CUPNH Uptake hydrogenase large subunit (Gene Name=hoxG)

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