Structure of PDB 5lez Chain L

Receptor sequence
>5lezL (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKT
VIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR
FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLD
NQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK
EGIREETVSLRKD
3D structure
PDB5lez The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
ChainL
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide L D125 V127 D125 V127
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5lez, PDBe:5lez, PDBj:5lez
PDBsum5lez
PubMed27493187
UniProtP20618|PSB1_HUMAN Proteasome subunit beta type-1 (Gene Name=PSMB1)

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