Structure of PDB 4yhm Chain L

Receptor sequence
>4yhmL (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
DIVMTQTPLSLSVTPGQPASISCRSSQSIVHSDGNIYLEWYLQKPGQSPK
LLIYKVSYRFSGVPDRFSGSGSGTGFTLKISRVEAEDVGVYYCFQASHVP
YTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
3D structure
PDB4yhm Structure-guided residence time optimization of a dabigatran reversal agent.
ChainL
Resolution2.16 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4CC L E39 A96 Y101 E39 A96 Y101 PDBbind-CN: -logKd/Ki=9.76,Kd=173pM
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