Structure of PDB 4ocx Chain L

Receptor sequence
>4ocxL (length=214) Species: 10090 (Mus musculus) [Search protein sequence]
DVLLTQIPLSLPVSLGDQASISCRSSQSIVHSNGNTYLEWYLQKPGQSPK
LLIYKVSTRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVP
LTFGAGTQLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDIN
VKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE
ATHKTSPIVKSFNR
3D structure
PDB4ocx Water channel in the binding site of a high affinity anti-methotrexate antibody.
ChainL
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MT1 L H31 Y37 E39 F94 G96 L101 H31 Y37 E39 F94 G96 L101 MOAD: Kd~3.6pM
PDBbind-CN: -logKd/Ki=11.44,Kd~3.6pM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4ocx, PDBe:4ocx, PDBj:4ocx
PDBsum4ocx
PubMed24832237
UniProtA2NHM3

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