Structure of PDB 4bks Chain L

Receptor sequence
>4bksL (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
VLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHS
YRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKER
CLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQER
3D structure
PDB4bks Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
ChainL
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X6C L W88 Y98 P99 R107 I109 H110 S111 H115 W117 W27 Y37 P38 R46 I48 H49 S50 H54 W56 MOAD: Kd=150uM
BindingDB: Kd=150000nM
External links
PDB RCSB:4bks, PDBe:4bks, PDBj:4bks
PDBsum4bks
PubMed24436777
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

[Back to BioLiP]