Structure of PDB 4b86 Chain L

Receptor sequence
>4b86L (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPVNATALYISASRLVLNYDPKAFTEINRLLPYFRQSLSCCVCGHLLQD
PIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCY
KKLCEYITQTTL
3D structure
PDB4b86 Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila.
ChainL
Resolution3.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN L C44 C47 C67 C41 C44 C64
BS02 ZN L C62 H64 C81 C84 C59 H61 C78 C81
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity
Cellular Component
GO:0072487 MSL complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4b86, PDBe:4b86, PDBj:4b86
PDBsum4b86
PubMed23084835
UniProtQ9HCI7|MSL2_HUMAN E3 ubiquitin-protein ligase MSL2 (Gene Name=MSL2)

[Back to BioLiP]