Structure of PDB 3wn7 Chain L

Receptor sequence
>3wn7L (length=286) Species: 10090 (Mus musculus) [Search protein sequence]
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGL
LYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDG
HIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLY
AVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAG
GYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYD
GHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVT
3D structure
PDB3wn7 Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1
ChainL
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide L Y334 R380 N382 D385 G386 N387 R415 S431 G433 H436 I461 R483 S555 A556 Y572 F577 S602 Y11 R57 N59 D62 G63 N64 R92 S108 G110 H113 I138 R160 S232 A233 Y249 F254 S279
External links
PDB RCSB:3wn7, PDBe:3wn7, PDBj:3wn7
PDBsum3wn7
PubMed24366543
UniProtQ9Z2X8|KEAP1_MOUSE Kelch-like ECH-associated protein 1 (Gene Name=Keap1)

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