Structure of PDB 3tyg Chain L

Receptor sequence
>3tygL (length=207) Species: 9606 (Homo sapiens) [Search protein sequence]
QSALTQPPSASGSPGQSITISCTGTSNNFVSWYQQHAGKAPKLVIYDVNK
RPSGVPDRFSGSKSGNTASLTVSGLQTDDEAVYYCGSLVGNWDVIFGGGT
KLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKAD
SSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGST
VEKTVAP
3D structure
PDB3tyg A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
ChainL
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN L N94 D95A N91 D93
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0016064 immunoglobulin mediated immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex
GO:0070062 extracellular exosome
GO:0071735 IgG immunoglobulin complex
GO:0072562 blood microparticle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3tyg, PDBe:3tyg, PDBj:3tyg
PDBsum3tyg
PubMed21998254
UniProtP0DOY2|IGLC2_HUMAN Immunoglobulin lambda constant 2 (Gene Name=IGLC2)

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