Structure of PDB 3th3 Chain L

Receptor sequence
>3th3L (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
GDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENG
GCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
3D structure
PDB3th3 Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+
ChainL
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUC L S60 L73 S14 L27
BS02 CA L G47 Q49 D63 Q64 G1 Q3 D17 Q18
BS03 BGC L Q49 S52 P54 Q3 S6 P8
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:3th3, PDBe:3th3, PDBj:3th3
PDBsum3th3
PubMed
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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