Structure of PDB 2ian Chain L

Receptor sequence
>2ianL (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVY
PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB2ian Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
ChainL
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide L L11 F13 D57 Y60 W61 Q70 R71 Y78 H81 N82 V85 L9 F11 D55 Y58 W59 Q68 R69 Y76 H79 N80 V83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2ian, PDBe:2ian, PDBj:2ian
PDBsum2ian
PubMed17334368
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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