Structure of PDB 2fir Chain L

Receptor sequence
>2firL (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQC
ASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQ
YCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
3D structure
PDB2fir High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: Unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+ and Zn2+ sites in factor VIIa
ChainL
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC L G58 S60 F71 C72 G58 S60 F71 C72
BS02 MG L E25 E29 E25 E29
BS03 CA L E26 E29 E26 E29
BS04 CA L E26 E29 E26 E29
BS05 MG L E16 E26 E16 E26
BS06 CA L A1 E16 E20 A1 E16 E20
BS07 CA L E6 E20 E6 E20
BS08 MG L E14 E19 E14 E19
BS09 CA L D46 G47 Q49 D63 Q64 D46 G47 Q49 D63 Q64
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2fir, PDBe:2fir, PDBj:2fir
PDBsum2fir
PubMed16757484
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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