Structure of PDB 2c0b Chain L

Receptor sequence
>2c0bL (length=488) Species: 562 (Escherichia coli) [Search protein sequence]
AHIEGRHMKRMLINATQQEELRVALVDGQRLYDLDIESPEQKKANIYKGK
ITRIEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDK
EERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIELKEALASLELPL
IVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVR
AFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLF
SHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARDIEETAFN
TNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDR
ARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSL
SILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRC
VIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEA
3D structure
PDB2c0b Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
ChainL
Resolution3.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna L F67 K106 K112 G113 G137 G138 I139 S140 I167 R169 T170 L342 R373 Q390 R391 F68 K100 K106 G107 G131 G132 I133 S134 I151 R153 T154 L321 R352 Q369 R370
BS02 ZN L C404 C407 C383 C386
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2c0b, PDBe:2c0b, PDBj:2c0b
PDBsum2c0b
PubMed16237448
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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