Structure of PDB 2bx2 Chain L

Receptor sequence
>2bx2L (length=500) Species: 562 (Escherichia coli) [Search protein sequence]
AHIEGRHMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYK
GKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEV
IVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIELKEALA
SLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFL
IHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKI
KLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINS
ARGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVE
NRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGT
GTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVN
AIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM
3D structure
PDB2bx2 Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
ChainL
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna L V128 A136 G137 G138 I139 S140 R141 I167 R169 T170 R373 V128 A136 G137 G138 I139 S140 R141 I161 R163 T164 R363
BS02 MG L D303 D346 D297 D336
BS03 ZN L C404 C407 C394 C397
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2bx2, PDBe:2bx2, PDBj:2bx2
PDBsum2bx2
PubMed16237448
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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