Structure of PDB 1z6j Chain L

Receptor sequence
>1z6jL (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQC
ASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQ
YCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
3D structure
PDB1z6j Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa.
ChainL
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA L D46 G47 Q49 D63 Q64 D46 G47 Q49 D63 Q64
BS02 MG L E14 E19 E14 E19
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1z6j, PDBe:1z6j, PDBj:1z6j
PDBsum1z6j
PubMed15913999
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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