Structure of PDB 1nb3 Chain L

Receptor sequence
>1nb3L (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
MIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAG
TNYYIKVRAGDNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF
3D structure
PDB1nb3 Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases
ChainL
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide L M6 I7 M1 I2
Gene Ontology
Molecular Function
GO:0002020 protease binding
GO:0004866 endopeptidase inhibitor activity
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0010466 negative regulation of peptidase activity
GO:0018149 peptide cross-linking
GO:0030216 keratinocyte differentiation
GO:0045861 negative regulation of proteolysis
GO:0098609 cell-cell adhesion
Cellular Component
GO:0001533 cornified envelope
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1904090 peptidase inhibitor complex

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External links
PDB RCSB:1nb3, PDBe:1nb3, PDBj:1nb3
PDBsum1nb3
PubMed12581647
UniProtP01040|CYTA_HUMAN Cystatin-A (Gene Name=CSTA)

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