Structure of PDB 1dan Chain L

Receptor sequence
>1danL (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQC
ASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQ
YCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILE
3D structure
PDB1dan The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.
ChainL
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC L Q49 S52 Q49 S52
BS02 CA L D46 G47 Q49 D63 Q64 D46 G47 Q49 D63 Q64
BS03 CA L E7 E26 E29 E7 E26 E29
BS04 CA L E7 E16 E26 E29 E7 E16 E26 E29
BS05 CA L A1 N2 E6 E7 E16 E26 A1 N2 E6 E7 E16 E26
BS06 CA L A1 E6 E16 E20 A1 E6 E16 E20
BS07 CA L E14 E19 E14 E19
BS08 CA L E25 E29 E25 E29
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:1dan, PDBe:1dan, PDBj:1dan
PDBsum1dan
PubMed8598903
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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