Structure of PDB 8xvg Chain K

Receptor sequence

>8xvgK (length=350) Species: 9606 (Homo sapiens) [Search protein sequence]

AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRAQSKRGILTLKYPIEHGI
VTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFE
TFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAI
LRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQ
EMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIH
ETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTM
KIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF

3D structure

PDB

8xvg Structure of the human TIP60 complex

Chain

Resolution

9.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	K	G13 S14 M16 K18 G156 D157 K213 E214 G302 M305	G8 S9 M11 K13 G131 D132 K188 E189 G277 M280

External links

PDB	RCSB:8xvg, PDBe:8xvg, PDBj:8xvg
PDBsum	8xvg
PubMed	39154037
UniProt	A0A7K5XZZ2

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