Structure of PDB 8x5d Chain K

Receptor sequence
>8x5dK (length=235) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPG
TSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVF
RDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFA
FSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGT
RGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
3D structure
PDB8x5d Mycobacterium tuberculosis type III-A CRISPR/Cas system crRNA and its maturation have atypical features.
ChainK
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna K G23 A24 T52 K55 R59 G89 D90 M95 F125 N127 A128 I129 L138 R139 Y195 G197 R202 G22 A23 T51 K54 R58 G88 D89 M94 F124 N126 A127 I128 L137 R138 Y194 G196 R201
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8x5d, PDBe:8x5d, PDBj:8x5d
PDBsum8x5d
PubMed38218299
UniProtP9WJF9|CSM3_MYCTU CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

[Back to BioLiP]