Structure of PDB 8x1c Chain K

Receptor sequence
>8x1cK (length=394) Species: 9606 (Homo sapiens) [Search protein sequence]
MTTLVLDNGAYNAKIGYSHENVSVIPNCQFRSKTARLKTFTANQIDEIKD
PSGLFYILPFQKGYLVNWDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYF
NFTSIQESMNEILFEEYQFQAVLRVNAGALSAHRYFRDNPSELCCIIVDS
GYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETH
VINQVKEDVCYVSQDFYRDMDIAKLKGEENTVMIDYVLPDFSTIKKGFCK
PREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVY
SIQNLPEEMQPHFFKNIVLTGGNSLFPGFRDRVYSEVRCLTPTDYDVSVV
LPENPITYAWEGGKLISENDDFEDMVVTREDYEENGHSVCEEKF
3D structure
PDB8x1c Structure of nucleosome-bound SRCAP-C in the ADP-bound state
ChainK
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP K G9 A10 Y11 G151 Y152 K206 E207 G322 N323 L325 G9 A10 Y11 G151 Y152 K206 E207 G322 N323 L325
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0031491 nucleosome binding
Biological Process
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0007000 nucleolus organization
GO:0016479 negative regulation of transcription by RNA polymerase I
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0000786 nucleosome
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton

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Cellular Component
External links
PDB RCSB:8x1c, PDBe:8x1c, PDBj:8x1c
PDBsum8x1c
PubMed38331872
UniProtQ9GZN1|ARP6_HUMAN Actin-related protein 6 (Gene Name=ACTR6)

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