Structure of PDB 8w7e Chain K

Receptor sequence
>8w7eK (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPI
HMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPG
MRHSLPNSRIMIHQPSAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAME
RDRYMSPMEAQEFGILDKVLVH
3D structure
PDB8w7e Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
ChainK
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9I3 K L104 S108 L39 S43
BS02 9I3 K E82 I84 H116 Y118 W146 V148 E17 I19 H51 Y53 W81 V83
External links
PDB RCSB:8w7e, PDBe:8w7e, PDBj:8w7e
PDBsum8w7e
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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