Structure of PDB 8utt Chain K

Receptor sequence
>8uttK (length=382) Species: 9606 (Homo sapiens) [Search protein sequence]
ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFD
YSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGK
SYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCER
VRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKAR
TVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSE
RADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDF
ILYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQ
IRCNAVINEDPNNKLIRELKDEVTRLRDLLYA
3D structure
PDB8utt Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
ChainK
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG K S104 S215 S101 S212
BS02 ANP K R11 R13 P14 G100 A101 G102 K103 S104 Y105 N211 S214 S215 R8 R10 P11 G97 A98 G99 K100 S101 Y102 N208 S211 S212
External links
PDB RCSB:8utt, PDBe:8utt, PDBj:8utt
PDBsum8utt
PubMed38956021
UniProtQ12756|KIF1A_HUMAN Kinesin-like protein KIF1A (Gene Name=KIF1A)

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