Structure of PDB 8u14 Chain K

Receptor sequence
>8u14K (length=88) Species: 9606 (Homo sapiens) [Search protein sequence]
AIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRR
RVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLRASG
3D structure
PDB8u14 Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2)
ChainK
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN K C31 H33 C51 C54 C25 H27 C45 C48
BS02 ZN K C16 C19 C10 C13
External links
PDB RCSB:8u14, PDBe:8u14, PDBj:8u14
PDBsum8u14
PubMed38242129
UniProtQ8IYW5|RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (Gene Name=RNF168)

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