Structure of PDB 8ttw Chain K

Receptor sequence
>8ttwK (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
QIHLVQSGTEVKKPGSSVTVSCKAYGVNTFGLYAVNWVRQAPGQSLEYIG
QIWRWKSSASHHFRGRVLISAVDLTGSSPPISSLEIKNLTSDDTAVYFCT
TTSTYDRWSGLHHDGVMAFSSWGQGTLISVSAASTKGPSVFPLAPSSTAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYICNVNHKPSNTKVDKRVEPK
3D structure
PDB8ttw Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
ChainK
Resolution2.96 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA K S70 A71 S70 A71
BS02 MAN K S70 A71 I77D S79 S70 A71 I81 S83
BS03 MAN K T19 S70 E81 T19 S70 E85
BS04 MAN K S57 G65 V67 S57 G65 V67
External links