Structure of PDB 8sr1 Chain K

Receptor sequence
>8sr1K (length=236) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence]
LLDKKWLTFALAIYTVFYLWVRWYEGVYGWSAGLDSFAPEFETYWMNFLY
TEIVLEIVTASILWGYLWKTRDRNLAALTPREELRRNFTHLVWLVAYAWA
IYWGASYFTEQDGTWHQTIVRDTDFTPSHIIEFYLSYPIYIITGFAAFIY
AKTRLPFFAKGISLPYLVLVVGPFMILPNVGLNEWGHTFWFMEELFVAPL
HYGFVIFGWLALAVMGTLTQTFYSFAQGGLGQSLCE
3D structure
PDB8sr1 Product analogue binding identifies the copper active site of particulate methane monooyxgenase
ChainK
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CU K N227 H231 H245 N183 H187 H201
BS02 HXG K W234 F235 M236 E237 P243 Y246 W190 F191 M192 E193 P199 Y202
BS03 HXG K L63 W67 Y146 Y151 L19 W23 Y102 Y107
BS04 WIY K D156 H160 R165 H231 E237 E238 L239 D112 H116 R121 H187 E193 E194 L195
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8sr1, PDBe:8sr1, PDBj:8sr1
PDBsum8sr1
PubMed38187819
UniProtQ603F1

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