Structure of PDB 8sna Chain K

Receptor sequence
>8snaK (length=85) Species: 9606 (Homo sapiens) [Search protein sequence]
AIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRR
RVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLR
3D structure
PDB8sna Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2)
ChainK
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN K C31 H33 C51 C54 C25 H27 C45 C48
BS02 ZN K C16 C19 C39 C10 C13 C33
External links
PDB RCSB:8sna, PDBe:8sna, PDBj:8sna
PDBsum8sna
PubMed38242129
UniProtQ8IYW5|RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (Gene Name=RNF168)

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