Structure of PDB 8smz Chain K

Receptor sequence
>8smzK (length=85) Species: 9606 (Homo sapiens) [Search protein sequence]
AIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRR
RVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKLR
3D structure
PDB8smz Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (Class 4)
ChainK
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN K C31 H33 C51 C54 C25 H27 C45 C48
BS02 ZN K C16 C19 C36 C10 C13 C30
External links
PDB RCSB:8smz, PDBe:8smz, PDBj:8smz
PDBsum8smz
PubMed38242129
UniProtQ8IYW5|RN168_HUMAN E3 ubiquitin-protein ligase RNF168 (Gene Name=RNF168)

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