Structure of PDB 8oeq Chain K

Receptor sequence

>8oeqK (length=203) Species: 5476 (Candida albicans) [Search protein sequence]

GISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGPKRIHSVRTRGG
NQKFRALRVETGNFSWGSEGVSRKTRIAGVVYHPSNNELVRTNTLTKSAV
VQIDATPFRQWYENHYGATLGKKKGGAHAAHAAEVADAKRSRKVERKLAA
RSGAAAIESAVDSQFGSGRLYAVISSRPGQSGRCDGYILEGEELAFYLRR
LTA

3D structure

PDB

8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	K	R77 E89 R92 D105 R110 K124 H129 F166 G167 S168 G169 R170	R76 E88 R91 D104 R109 K123 H128 F165 G166 S167 G168 R169
BS02	rna	K	G2 I3 R5 R8 H9 K10 R11 A13 T14 G15 A16 R18 F21 R22 K23 K24 R25 K26 F27 L29 G30 R31 Q32 P33 A34 R42 I43 H44 R47 T48 R49 G50 G51 N52 K54 R56 R59 N64 S66 V72 S73 R74 K75 S86 N87 T97 K98 S99 N115 K140 R141 S142 R143 K144 V145 R147 K148 A151 R152 S176 R178 G180 Q181 S182 R184 D186	G1 I2 R4 R7 H8 K9 R10 A12 T13 G14 A15 R17 F20 R21 K22 K23 R24 K25 F26 L28 G29 R30 Q31 P32 A33 R41 I42 H43 R46 T47 R48 G49 G50 N51 K53 R55 R58 N63 S65 V71 S72 R73 K74 S85 N86 T96 K97 S98 N114 K139 R140 S141 R142 K143 V144 R146 K147 A150 R151 S175 R177 G179 Q180 S181 R183 D185
BS03	MG	K	V91 N94	V90 N93

External links

PDB	RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum	8oeq
PubMed
UniProt	A0A8H6F0S0

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