Structure of PDB 8imx Chain K

Receptor sequence
>8imxK (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
GHTNNWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDM
ACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIP
PSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADAFEQM
WQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPA
IGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDL
FQRDPKNVLITDFFGSVRKVEITTETIKLQKLMEPLKYAEQLPVAQIIHQ
KPKLKDWHPPGGFILGLWALIIMVFFKTYG
3D structure
PDB8imx Structures of substrates- and products-bound glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis
ChainK
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide K G165 F169 K171 E177 G125 F129 K131 E137
BS02 peptide K R60 C206 S232 L233 S234 H244 R20 C166 S192 L193 S194 H204
BS03 CA K D79 I82 E118 D120 D39 I42 E78 D80
Gene Ontology
Molecular Function
GO:0003923 GPI-anchor transamidase activity
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008218 bioluminescence
GO:0016255 attachment of GPI anchor to protein
Cellular Component
GO:0042765 GPI-anchor transamidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8imx, PDBe:8imx, PDBj:8imx
PDBsum8imx
PubMed37684232
UniProtQ92643|GPI8_HUMAN GPI-anchor transamidase (Gene Name=PIGK)

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