Structure of PDB 8dsj Chain K

Receptor sequence
>8dsjK (length=306) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NECGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFK
PRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPT
RLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQ
PLIAGMYLMMSVDTVIPPGEKVVNADISCQYKMYPMHVFAYRVHTHHLGK
VVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGE
GRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTCTKNVAPDMFRTIPA
EANIPI
3D structure
PDB8dsj New structures reveal flexible dynamics between the subdomains of peptidylglycine monooxygenase. Implications for an open to closed mechanism.
ChainK
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.17.3: peptidylglycine monooxygenase.
4.3.2.5: peptidylamidoglycolate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU K H107 H108 H172 H59 H60 H124
BS02 CU K H242 H244 M314 H194 H196 M266
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004497 monooxygenase activity
GO:0005507 copper ion binding
GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
Biological Process
GO:0006518 peptide metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8dsj, PDBe:8dsj, PDBj:8dsj
PDBsum8dsj
PubMed36880254
UniProtP14925|AMD_RAT Peptidylglycine alpha-amidating monooxygenase (Gene Name=Pam)

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